Santiago Cuba.This is the base from which Fidel Castro and Che Guevara launched their revolutionary movement in the 1950s. Santiago de Cuba has inspired writers, musicians, politicians, and architects to create memorable Cuban masterpieces. Visit the Basilica de Nuestra Señora de la Caridad del Cobre, Cuba’s most sacred pilgrimage site, or see the 17th-century castle overlooking Santiago Bay at dusk.